Tsp1 thbs1
WebAug 1, 2024 · The LSKL peptide is a competitive antagonist that inhibits TSP-1-TGF-β activation by preventing the interaction of TSP-1's KRFK sequence with the LAP of latent TGF-β (Fig. 1) [23].This antagonist tetrapeptide has been widely used by our lab and others, along with thbs1 (TSP-1) null animals, to establish TSP-1 as a primary regulator of TGF-β … WebTHBS, THBS-1, THBS1, TSP, TSP-1, TSP1. Gene ID (Human) 7057. Gene symbol. THBS1. UniProt ID (Human) P07996. Show Less . About This Kit. The Human Thrombospondin-1 (Hu TSP-1) ELISA quantitates Hu TSP-1 in human serum or plasma. The assay will exclusively recognize both natural and recombinant Hu TSP-1.
Tsp1 thbs1
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WebThrombospondin 1 (TSP1 or THBS1) Somatostatin Receptor (SSTR) Insulin Receptor (IR or CD220 or INSR or EC 2.7.10.1) WebThe adhesive glycoprotein thrombospondin-1 (THBS1, TSP1) localizes to the extracellular matrix (ECM) and mediates interactions between cells and the ECM and among cells. Thrombospondin-1 is a multi-domain, glycosylated protein that interacts with a wide variety of extracellular targets, including matrix metalloproteinases (MMPs), collagens, cell …
WebApr 14, 2024 · Recent advances provide evidence that the cellular signalling pathway comprising the ligand-receptor duo of thrombospondin-1 (TSP1) and CD47 is involved in mediating a range of diseases affecting renal, vascular, and metabolic function, as well as cancer. In several instances, research has barely progressed past pre-clinical animal … WebOct 31, 2006 · Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS1 with CD36 (PubMed:11134179). Interacts with ATF6 (via …
WebMar 8, 2024 · Thrombospondin-1 (THSB1) is a component of the ECM with a role in regulating cancer development and tumour vasculature. Here, the authors show that TGF-beta-induced THBS1 expression contributes to ... Web006141 B6.129S2- Thbs1 tm1Hyn /J Mice homozygous for this targeted mutation exhibit an increase in the number of circulating white blood cells with monocytes and eosinophils …
WebMar 21, 2024 · THBS1 (Thrombospondin 1) is a Protein Coding gene. Diseases associated with THBS1 include Thrombotic Thrombocytopenic Purpura and …
WebApr 5, 2024 · LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1. Genetic regulation of THBS1 methylation in diabetic … how close is oahu to honoluluWebApr 9, 2024 · Recombinant Human THBS1, N-His Summary Catalog No. YHC29401 Alternative Names TSP, THBS1, TSP1, Thrombospondin-1, Glycoprotein G Form Lyophilized Storage buffer Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Purity >90% as determined by SDS-PAGE. how many players in nbaWebApr 27, 2024 · In addition to an intrinsic role for TSP1 expressed by tumor cells, increased growth of B16 melanomas and F9 testicular teratocarcinomas was observed when implanted in syngeneic mouse strains lacking Thbs1 . As TSP1 is a secreted protein, its abundance in the tumor microenvironment depends on both tumor and stromal cell … how many players in monopolyWebJun 25, 2024 · Conversely, male and female Thbs1-null mice showed less weight gain after 5 mo on an HFD or high-carbohydrate/low-fat diet compared with wild-type mice , indicating that the effects of TSP1 on fat-induced weight gain may be time dependent. Obesity-related renal impairment was less in 6-mo-old Thbs1- and Cd36-null mice . how many players in nba currentlyWebJan 27, 2016 · Infiltration of CD68 + macrophages into liver tissue after ischemia/reperfusion injury was similarly reduced in thbs1 −/− and cd47 −/− mice, … how many players in lacrossehttp://yobibio.com/product.asp?anclassid=8&nclassid=53&bookid=4838 how many players in overcooked 2WebThe adhesive glycoprotein thrombospondin-1 (THBS1, TSP1) localizes to the extracellular matrix (ECM) and mediates interactions between cells and the ECM and among cells. … how many players in monopoly game