Siglectf
WebDescription: This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds … WebThe important finding that deleting Mo-AMs within an injured lung can lessen the severity of fibrosis represents a significant advance in the field (14 and 15).Although many groups have shown that mice with systemic monocytopenia (i.e., mice given intravenous liposomal clodronate, CCR2 −/− mice, and CEPBδ −/− mice) are protected against fibrosis (8, 16, 17), …
Siglectf
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WebOct 7, 2016 · Here, using a monoclonal antibody we generated to the Sialic acid-binding immunoglobulin-like lectin F (Siglec-F), we show that Siglec-F is expressed on mouse M … Web丁香通，丁香园旗下专业的生物医药商业信息平台，拥有试剂抗体、仪器耗材、医疗设备、辅料原料药等各类产品供求信息近300万条，致力为医药企业和生物医药相关行业人士建立联系的桥梁和纽带，提供购销渠道以及优质服务，满足会员供应采购、合作转让招商代理、信息资讯查询等各类营销及 ...
WebThrough binding ubiquitous sialic-acid residues on cell surfaces, the Siglec family of lectins promote cell–cell interactions and regulate the functions of numerous immune-cell types. … WebCD170, also known as Siglec-F, Siglec-5, is a member of the Sialic acid-binding Ig-like lectin family, type I single pass transmembrane protein, with 4 extracellular Ig-like domains and …
WebGlobo-系列醣體被認為與癌症的演進有很高的關聯性。這些醣體之中，DSGb5被發現大量表達於腎細胞癌 (RCC) 且與 RCC 的轉移有關；而在乳癌細胞表面則大量表現 Gb5、SSEA4以及 Globo H。除外，唾液酸常被發現存在於細胞表面醣體的末端。唾液酸免疫球蛋白凝集素 (Siglecs) 藉由辨識病原體表面的唾液酸來調節 ... WebApr 10, 2024 · The emerging importance of the Siglec-sialic acid axis in human disease, especially cancer, has necessitated the identification of ligands for Siglecs. Recombinant …
WebJun 22, 2005 · Analysis of sialoside specificity of Siglec-F. To understand the structural requirement of 6′-sulfo-sLe X that confers increased affinity to Siglec-F, we further verified the glycan array results by reverse assay using various sialylated oligosaccharides coupled to polyacrylamide backbones (sialoside-PAA probes) and immobilized Siglec-F-Fc chimera.
WebMouse Fc Block™ (purified anti-mouse CD16/CD32 mAb 2.4G2, Cat. No. 553141/553142) may help to reduce non-specific binding to cells bearing Fcγ receptors. If Mouse Fc … how to start a facebookWeb丁香通，丁香园旗下专业的生物医药商业信息平台，拥有试剂抗体、仪器耗材、医疗设备、辅料原料药等各类产品供求信息近300万条，致力为医药企业和生物医药相关行业人士建立 … reach tiny homes sewttleWebApr 13, 2024 · A critical element that helps the dendritic cells recognize and bind to the virus is a group of membrane proteins that distinguish between self and non-self. One such protein, called Siglec-1 ... how to start a eyelash brand businessWebApr 10, 2024 · The emerging importance of the Siglec-sialic acid axis in human disease, especially cancer, has necessitated the identification of ligands for Siglecs. Recombinant Siglec-Fc fusion proteins have been widely used as ligand detectors, and also as sialic acid-targeted antibody-like proteins for cancer treatment. However, the heterogenetic … reach tire and auto kelownaWebDendritic cells (DCs) are among the first cells that recognize incoming viruses at the mucosal portals of entry. Initial interaction between DCs and viruses facilitates cell activation and migration to secondary lymphoid tissues, where these antigen presenting cells (APCs) prime specific adaptive immune responses. Some viruses, however, have … how to start a fab shopWebSiglecs (sialic acid-binding, Ig-like lectins) are a family of single-pass transmembrane cell surface proteins found predominantly on leucocytes. Their unique structural … how to start a facebook conversationWebOct 5, 2024 · Eosinophil recruitment in asthma is a multistep process, involving both trans-endothelial migration to the lung interstitium and trans-epithelial migration into the … how to start a facial spa business