Phospho irf7

Author: zuwx

August undefined, 2024

WebJan 3, 2014 · An anti-phospho-IRF7 antibody was used for detection of phosphorylated form of IRF7. IRF7 was present predominantly in an unphosphorylated form in cells transfected with IRF7 alone . Co-expression of MyD88, TRAF6 and IKKα enhanced the level of phosphorylated IRF7, whereas this enhancement was strikingly suppressed by co … WebDimerization of Phospho IRF3 or phospho IRF7. Phosphorylation of these transcription factors IRF3 and IRF7 results in a conformational change that allows their dimerization to form homo- or hetero dimers. Each of the three different combinations of dimers (IRF3:IRF3, IRF7:IRF7 and IRF3:IRF7) may selectively effect the transcription of IFN-alpha ...

小鼠牛小肠碱性磷酸酶(CIAP)检测试剂盒-,小鼠牛小肠碱性磷酸酶研 …

WebIRF7: Gene ID: 3665: Uniprot ID: IRF7_HUMAN: Specificity: Phospho-IRF7-Ser471/472 polyclonal antibody (Interferon Regulatory Factor 7) binds to endogenous Interferon … WebSep 1, 2024 · Irf3-/-Irf7-/- MEFs were seeded on 24-well plates (1 ×10 5 cells/well) and transfected the following day with 50 ng of luciferase reporter plasmid together with 0.8 μg of expression plasmid or empty control plasmid via Lipofectamine 2000 (Invitrogen). grand suite enchantment of the seas

Phospho-IRF-7 (Ser471/472) Antibody Cell Signaling Technology

WebNov 29, 2024 · IFN-I is the key regulatory component activating and modulating the response of innate and adaptive immune system to bacterial as well as viral pathogens. IFN-I promotes the expression of IFN-induced genes (ISG) and, consequently, the production of chemokines, e.g., CXCL10. Those chemokines control migration and localization of … WebSep 16, 2024 · The mice were intraperitoneally administrated with 100 mg fucoidan at 0, 1, 3, 5, and 7 days post-infection. e Phospho-ERK, total ERK, phospho-IRF7, and total IRF7 in the liver tissue of infected mice were examined by western blotting at the indicated days post-infection. f The production of IFN-α in the serum was evaluated by ELISA analysis. * p … WebPhospho-IRF-7 (Ser471/472) Antibody detects transfected levels of IRF-7 when phosphorylated at Ser471 and 472. Species Reactivity: Human Source / Purification … grand suite on carnival elation

Phospho-IRF7 (Ser471/Ser472) Antibody Affinity Biosciences

IRF-7 Antibody, anti-human, REAfinity™ - Miltenyi Biotec

WebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt. Alias: Fold/Unfold WebMethods: We evaluated the immunohistochemical (IHC) expression of Toll-like receptors 3-7-8-9 (TLR-3-7-8-9), TIR domain-containing adaptor inducing IFNÎ² (TRIF), Interferon regulatory factor 3 (IRF3), Phospho interferon regulatory factor 3 (pIRF3), Interferon regulatory factor 7 (IRF7), Phospho interferon regulatory factor 7 (pIRF7), retinoic ... grand sud immobilier bastiaWeb精脒;精胺N1-乙酰基转移酶1ELISA检测试剂盒相关名称：人淋巴毒素αLTA （Human lymphotoxin Alpha,LTA） ELISA Kit 96T 鱼类状腺原氨酸Fish i-iodothyronine,T3 ELISA Kit 96T grand suite 2 bedroom mariner of the seas

"WebFeb 21, 2024 · IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. " - Phospho irf7

Phospho irf7

Phosphorylation of Ser82 on IRF3 acts as negative-feedback …

WebPhospho-IRF-7 (Ser477) (D7E1W) Rabbit mAb recognizes endogenous levels of IRF-7 protein only when phosphorylated at Ser477. This antibody can also detect IRF-7 when … WebIRF7 was originally cloned as a factor that bound to a promoter region in the Epstein-Barr virus using a yeast one-hybrid system (Zhang and Pagano, 1997 ). IRF7, once induced, is …

Did you know?

WebClone REA310 recognizes the interferon regulatory factor 7 (IRF-7) phosphorylated at serines 477 and 479 (pS477/pS479). IRF-7 is a member of the IRF family of transcription factors and a key player in the innate immune response against viral infections. Constitutive expression of IRF-7 is limited to peripheral blood lymphocytes and dendritic cells while in … WebPhospho-IRF7-Ser471/472 polyclonal antibody (Interferon Regulatory Factor 7) binds to endogenous Interferon Regulatory Factor 7 only when phosphorylated at Ser471/472. Immunogen: Synthesized phosho peptide around human IRF-7 (Ser471 and 472) Post Translational Modifications :

WebOct 7, 2015 · We performed western blot analyses of phospho-IRF3 (p-IRF3), p-IRF7 and NF-κB (p–65) on protein samples from lung homogenates isolated from WT, NOD2-/-and IPS–1-/-mice infected with IAV and treated with LTB 4. LTB 4 alone did not influence the expression of IRF3 and IRF7 while it slightly enhances expression levels of p–65 (Fig 3A, 3B ... WebJul 7, 2024 · Colocalization of DNA with ubiquitin and phospho-TBK1 was also defective in Gt and ∆CTT cells but was normal in S365A cells ... It remains possible that IRF7, a homolog of IRF3, compensates for ...

WebDec 30, 2013 · As shown in Fig. 2 D, the MC160 protein prevented IRF7 activation because phospho-IRF7 levels were greatly diminished in MC160-expressing cells versus vector-transfected cells. In contrast, the MC159 protein did not inhibit IRF7 activation under these conditions: phospho-IRF7 levels were similar in pMC159- versus pCI-transfected cells. WebMar 29, 2024 · The juxtaposition of both the ubiquitination site and phospho-acceptor site on IRF7 and other IRFs suggests that such these post-translational modifications work sequentially to recruit in all the players necessary for activation. And similar to STING, it appears that competing ubiquitin or ubiquitin-like modifications work to fine-tune and ...

WebSee all IRF7 primary antibodies Description Rabbit polyclonal to IRF7 Host species Rabbit Tested applications Suitable for: IHC-P more details Species reactivity Reacts with: …

WebOct 7, 2012 · Because commercially available phosphospecific IRF7 antibodies are only sufficiently sensitive to detect overexpressed IRF7, we characterized the poly (I:C)-induced phosphorylation of IRF7... chinese restaurant on krewstown rdWebSep 13, 2012 · Baseline levels of phosphorylated IRF7 were found to be similar between males and females. However we observed faster phosphorylation kinetics of IRF7 in females than in males using flow cytometry with phospho-IRF7 peaking in females at 20min post-stimulation and males at 30min. grand suite navigator of the seasWeb丁香通为您找到78条tbk1抗体信息，包括tbk1抗体报价行情，优质供应商，图片，品牌等最新信息，丁香通为买家提供用户服务，诚信保障等服务，批发采购tbk1抗体,上丁香通。 grand suite oasis of the seasWebIRF-7 Antibody, anti-human, PE, REAfinity™ Data sheet 100 tests in 1 mL (1) ICFC, MICS, IF, IHC USD 310.00 Add to cart Other sizes 130-108-905 For research use only IRF-7 Antibody, anti-human, PE, REAfinity™ Data sheet 30 tests in 300 µL (1) ICFC, MICS, IF, IHC USD 110.00 Add to cart Applications Specifications Resources References grand suite one bedroom royal caribbeanWebIRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune … grand suite 2 bedroom adventure of the seasWebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: … grand suite 2 bedroom anthem of the seas chinese restaurant on lake street in addison