Webcell volume, that is a shrinking effect at lower Nigericin concentrations and a swelling effect at higher concentrations. Nigericin (0.1-1 nM) significantly decreases cytosolic pH (pHi), and slightly increases the pHi at 5 and 10 nM[2]. Nigericin exhibits higher toxicity on S18 cells than S26 cells, with IC50 of 2.03±0.55 μM and 4.77±2.35 ... WebAcidification of the cytoplasm of Ehrlich ascites carcinoma cells to pH 6.3 arrests DNA synthesis in these cells. Such an effect can be achieved by incubating the cells at pH 6.2 or by adding low concentrations of the K+/H+ antiporter, the antibiotic nigericin, at neutral pH. Glucose and anaerobiosis potentiate the nigericin effect.
Магній у біології — Вікіпедія
WebAug 2, 2016 · Nigericin (0.1-10 nM) has apparently a dual effect on cell volume, that is a shrinking effect at lower Nigericin concentrations and a swelling effect at higher concentrations. Nigericin (0.1-1 nM) significantly decreases cytosolic pH (pHi), and slightly increases the pHi at 5 and 10 nM. Nigericin exhibits higher toxicity on S18 cells than S26 ... http://www.cnreagent.com/s/sv75647.html csm mazzacorati bologna
ADAM10 Cell Surface Expression but Not Activity Is Critical for
WebJan 3, 2024 · The levels of IL-1β release were close to nigericin, a potent inflammasome activator due to its ability to induce potassium efflux. We found that these activators induced caspase-1 activation and... WebExplain the effects of increasing nigericin concentration on membrane potential ( ΔΨ) and the pH gradient (ΔpH).[6 marks] In a separate experiment, valinomycin was added to the same bacterial cells. The potassium concentration was varied, and the membrane potential (shown as circles) and pH gradient (shown as triangles) were also recorded. WebApr 11, 2024 · For further exploration the important effect of pyroptosis on the pathogenesis of endometritis and intervention role of TFC, LPS combined with nigericin to induce MEECs was used to establish a pyroptosis model of endometritis cells in vitro. Nigericin, a rapid and potent inducer of cell death, enhances the activation of NLRP3 inflammasome, and ... csm mazzacurati