High affinity copper uptake protein 1

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August undefined, 2024

WebCrystal structure of the high-affinity copper transporter Ctr1 PDB DOI: 10.2210/pdb6M97/pdb Classification: TRANSPORT PROTEIN Organism (s): Salmo salar, Escherichia coli Expression System: Komagataella phaffii GS115 Mutation (s): Yes Membrane Protein: Yes OPM PDBTM MemProtMD mpstruc Deposited: 2024-08-22 … Web1 de abr. de 2002 · Copper uptake High-affinity copper transport proteins Physiological and biochemical studies many years ago suggested the presence of at least two independent activities responsible for copper uptake in eukaryotic cells, of distinct affinities and capacities for copper [6].

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WebLOC106152599 high affinity copper uptake protein 1 [] Gene ID: 106152599, updated on 10-May-2024. Summary Other designations. high affinity ... on what principle does a pinhole camera work

Copper Stress Affects Iron Homeostasis by Destabilizing Iron …

Web1 de abr. de 2024 · The CTR1 gene of Saccharomyces cerevisiae encodes a protein required for high affinity copper uptake. The protein is expressed on the plasma membrane, is heavily glycosylated with O-linkages, and ... WebIn normal intestinal epithelial cells (left), copper (Cu) [depicted as brown circles] is mainly imported via the high-affinity transporter CTR1. Intracellular Cu is then transported to the mitochondria and the trans-Golgi network (TGN), where it … Webof Cu distribution. For example, the high affinity copper uptake protein 1 (CTR1) transports Cu in to cells at the plasma membrane. 12 The Cu-transporters ATP7A and ATP7B mediate the distribution of Cu to secreted cuproenzymes and Cu export. 13–20 ATP7A and ATP7B are highly homologous transporters that belong to the P 1B-family of … iot store perth

High affinity copper uptake protein 1 (Norway rat) - PubChem

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Web8 de jul. de 1997 · We propose this gene as a candidate for high-affinity copper uptake in humans and by analogy have named it h CTR1. The hCTR1 and yeast CTR1 predicted transmembrane proteins are 29% identical, but the human protein is substantially smaller in both the extracellular metal-binding and intracellular domains. WebCopper (Cu) is an essential trace element for growth and development and abnormal Cu levels are associated with anemia, metabolic disease and cancer. Evolutionarily … iot strategy pptWebGene ID: 105284566, updated on 12-Aug-2024. Summary Other designations. high affinity copper uptake protein 1 iot stethoscope

"Web1 de mar. de 2024 · Cu homeostasis is maintained by many chaperone proteins and transport carriers (Kim et al., 2008 ). For example, high affinity copper uptake protein 1 (CTR1) is a high-affinity Cu transporter which is located on cell membranes to uptake extracellular Cu ions ( Lee et al., 2002 ). " - High affinity copper uptake protein 1

High affinity copper uptake protein 1

Full article: Targeting copper metabolism to defeat KRAS-driven ...

http://www.cloud-clone.com/products/MAE493Hu21.html WebProtein target information for High affinity copper uptake protein 1 (house mouse). Find diseases associated with this biological target and compounds tested against it in …

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WebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 … Web30 de mar. de 2024 · Functional assays revealed that it stimulates the initial rate of radiolabeled copper uptake. CTR1 transports copper with high affinity in a time-dependent and saturable manner and is copper-specific. Transport is an energy-independent process and is stimulated by extracellular acidic pH and high K+ …

WebHMDBP08240. Secondary Accession Numbers. 13952. Name. High affinity copper uptake protein 1. Synonyms. Copper transporter 1. Solute carrier family 31 member 1. hCTR1. WebProtein target information for High affinity copper uptake protein 1 (Norway rat). Find diseases associated with this biological target and compounds tested against it in …

Web22 de out. de 2024 · One may speculate about copper speciation and/or mechanisms of copper uptake and release. Apart from trafficking in complex with various neurotransmitters, carrier peptides and proteins, or as part of the protein cargo of extracellular vesicles there is also the potential for copper uptake as a result of … Web15 de abr. de 2024 · High affinity copper uptake protein 1 (pig) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS …

Web12 de abr. de 2024 · To overcome this challenge, bacteria synthesize high-affinity iron-binding molecules called siderophores, which are recognized by specific transporters on the cell surface. Trojan horse antibiotics have evolved to hijack these transporters for uptake across the outer membrane (OM).

WebChemokines and chemokine receptors have been recognized as critical signal components that maintain the physiological functions of various cells, particularly the immune cells. The signals of chemokines/chemokine receptors guide various leukocytes to respond to inflammatory reactions and infectious agents. Many chemokine receptors play supportive … iot stock price historyWeb30 de dez. de 2005 · High affinity copper binding by wild type PrP has been confirmed by the independent techniques indicating the presence of specific tight copper binding sites … on what quadrant is the liver locatedWeb8 de abr. de 2024 · CLR01 treatment accelerated the soluble protein clearance, which ameliorated motor deficits in the PD mouse model [185]. α-synuclein aggregation is connected to the development of incurable multiple system atrophy (MSA). CLR01 doses decreased the number of α-synuclein high-molecular-weight oligomers and seeds in the … iot subscription boxWebAntigen: High affinity copper uptake protein 1 Available to For-Profits: Yes Antigen Species: Human Hybridoma Cells Available (Non-Profit): No Isotype: MIgG2b Depositor: Clinical Proteomics Technologies for Cancer Host Species: mouse Antigen Sequence: Positive Tested Species Reactivity: Human Depositors Institution: National Cancer Institute iot sub topicsWebLOC105369026 high affinity copper uptake protein 1 [] Gene ID: 105369026, updated on 13-Feb-2024. Summary Other designations. high affinity ... on what ranch is yellowstone filmedWebCPTC-SLC31A1-1 was deposited to the DSHB by Clinical Proteomics Technologies for Cancer (DSHB Hybridoma Product CPTC-SLC31A1-1) Storage and Handling … iot subject syllabusWeb8 de jul. de 1997 · It is concluded that CTR1 is the primary avenue for copper uptake in mammalian cells and is ubiquitously transcribed with highest expression observed in the specialized epithelia of the choroid plexus and renal tubules and in connective tissues of the eye, ovary, and testes. 351 PDF iot subnet