Hif 1α抗体
Web12 de jun. de 2024 · Hypoxia up-regulate PD-L1 expression via HIF-1α in glioma cell lines and combination treatment with HIF-1α inhibitor and anti–PD-L1 antibody can reduce tumor growth in murine model of glioma. a qPCR analysis of HIF-1α and PD-L1 mRNA expression in U251 and U343 lines with different treatments as indicated. The qPCR data were … Web缺氧诱导因子-1α(hypoxia-inducible factor 1α, HIF-1α)属于氧依赖的转录激活因子,在缺氧条件下HIF-1α的转录水平升高,参与肿瘤的生长及侵袭过程[4]。肺腺癌的靶向治疗目前已取得突破性进展,但仍有部分患者不能采用靶向治疗,对于这部分患者我们需要探索新的方法。
Hif 1α抗体
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WebHIF1A Antibodies. Antibodies that detect HIF1A can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow … Web16 de fev. de 2024 · HIF-1α Antibody Cell Signaling Technology 3716 product information product summary company name : Cell Signaling Technology product type : antibody product name : HIF-1α Antibody catalog : 3716 clonality : polyclonal host : rabbit conjugate : nonconjugated reactivity : human application : western blot, immunohistochemistry more …
WebUnder normoxic conditions, HIF-1 alpha is largely undetectable. Hypoxia needs to be induced in most cells and normal tissues. Location Cytoplasmic in normoxic conditions. … WebHIF1 regulates the transcription of a broad range of genes that facilitate responses to the hypoxic environment, including genes regulating angiogenesis, erythropoiesis, cell cycle, metabolism, and apoptosis. The widely expressed HIF-1α is typically degraded rapidly in normoxic cells by the ubiquitin/proteasomal pathway.
Web13 de fev. de 2014 · 1.2 主要试剂与仪器兔抗HIF-1α单克隆抗体(货号:ab51608)、鼠抗VEGF单克隆抗体(货号:ab1316)购自英国Abcam公司;TRIzol Reagent(美国Invitrogen公司);逆转录试剂盒(美国ThermoFish公司);GAPDH引物合成(上海生工生物工程技术服务公司);低压氧舱(上海减压器厂);ZH-ZYQ型自由落体脑损伤模型打 … Web30 de jul. de 2024 · A group of novel HIF-1α inhibitors, glyceollins, blocks HIF-1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding. J Cell Physiol. 2015;230:853–62.
Web11 de abr. de 2024 · 上海恒远生物科技有限公司供应人抗软骨抗体ELISA试剂盒供应产品,人抗软骨抗体ELISA试剂盒 英文名称:Human anti-cartilage-antibody ELISA KIT编号:HY20414E试剂盒内容及其配制试剂盒成份(2-8℃保存) 96孔配置 48孔 ... 生物素标记的抗HIF-1α抗体 1瓶(6ml) 1瓶(3 ...
Web缺氧诱导因子-1α(hypoxia-inducible factor 1α, HIF-1α)属于氧依赖的转录激活因子,在缺氧条件下HIF-1α的转录水平升高,参与肿瘤的生长及侵袭过程[4]。肺腺癌的靶向治疗目前已 … raymond formal shirtsWebMonoclonal Antibody for studying HIF1A. Cited in 31 publications. Validated for WB, IP, IF, F. Available in 2 sizes. Highly specific and rigorously validated in-house, HIF-1α (D5F3M) Mouse Monoclonal Antibody (CST … raymond formal trouser for menWeb近年来肝癌的发病率有所上升,尤其是肝细胞癌(HCC),而肝癌干细胞(liver cancer stem cells,LCSC)在HCC的发生发展中起着关键作用[1]。LCSC又称为肝癌起动细胞,是一 … simplicity\u0027s 3rWebNuclear HIF-1 engages p300/CBP for binding to hypoxic response elements (HREs). This process induces transcription and regulation of genes including EPO, VEGF, iNOS2, … raymond formal suitWeb23 de jul. de 2024 · HIF-1α Antibody (28b) is an IgG 1 κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the … raymond forniWeb15 de fev. de 2008 · HIF-1 α controls metabolic and pH-regulating pathways. Cells respond to hypoxia by HIF-1 α -mediated upregulation of glucose transporters (Glut-1 and Glut-3) and enzymes of glycolysis.... simplicity\\u0027s 3rWeb缺氧诱导因子(HIF)是转录因子,能对细胞环境中可用氧的变化做出反应,尤其是对氧气的减少或缺氧做出反应。. HIF-1α 调控着 40 多种基因的转录,包括促红细胞生成素、葡萄 … simplicity\\u0027s 3t