WebAptamers, often termed “chemical antibodies”, are functionally similar to antibodies and have demonstrated their superiority of recognizing target with high selectivity, affinity and stability. With these intrinsic properties, aptamers have been widely studied in cancer biology and some are in clinical trials. WebAptamer is an artificial chemical antibody that is generated from the randomized nucleic acid library by three simple steps: binding, separation, and amplification. The selected …

Electrochemical detection of human epidermal growth factor

Webmediator, immobilization platform for an HB5 aptamer and to enhance the electrochemical signal for the detection of HER2. Furthermore, the CoTAPc was combined individually with graphene quantum dots (SNGQDs), gold nanoparticles (AuNPs) and cerium oxide nanoparticles (CeO2NPs), on a glassy carbon electrode (GCE) via sequential adsorption. Web15 apr 2014 · Aptamers are single-stranded oligonucleotides which can specifically recognize and bind to target cells by distinct secondary and tertiary structures even without knowledge of characteristic... gwynedd endodontics

RCSB PDB - 5DO4: Thrombin-RNA aptamer complex

Web21 set 2024 · MXene-based cytosensor for the detection of HER2-positive cancer cells using CoFe 2 O 4@Ag magnetic nanohybrids conjugated to the HB5 aptamer MXene-based … WebIn the work, an aptamer modified terahertz (THz) metasurface (MS) biosensor is proposed to specifically detect the human epidermal growth factor receptor 2 (HER2) which is a typical label of breast cancer. The biosensor is an array structure consisting of two metal split-ring-resonators (SRRs) in a unit cell. Compared with the conventional SRRs directly … WebHB5 Aptamer [3] and H2 Aptamer [4]. For convenience, we rename HB5 Aptamer to HR2 Aptamer. Both aptamers are selected through SELEX. H2 Aptamer is used to coat … gwynedd estates beauty salon