WebJun 23, 2024 · National Center for Biotechnology Information WebAccumulation is inversely proportional to the fraction of the dose lost in each dosing interval. The fraction lost is 1 minus the fraction remaining just before the next dose. The fraction remaining can be predicted from the dosing interval and the half-life. A convenient index of accumulation is the accumula-tion factor:

Drug Tolerance: What It Is, What to Do About It & More - Healthline

Web1. To gather in a heap; accumulate. 2. To combine into one unit; merge. v.intr. To become massed. adj. Having cumulated or having been cumulated; heaped up or amassed. … WebNov 27, 2009 · The general pharmacology is involves the aspects of sources of drugs, route of administration of drugs, absorption of drugs and factors affecting them, distribution, bio-transformation and excretion. It also involves the mechanism by which drug is acting with receptor, toxicity of drug and preclinical & clinical evaluation. Pharmacology great places to go with bed and breakfasts

Cumulative definition of cumulative by Medical dictionary

Web4-Cumulative drug effect 5-Toxic reactions 6-pharmacogenetic reactions Cumulative drug effect Definition: The condition in which repeated administration of a drug may produce effects that are more pronounced than those produced by the first dose. A cumulative drug effect may be seen in those with liver or kidney disease because these Webnoun the act of cumulating; accumulation. a heap; mass. There are grammar debates that never die; and the ones highlighted in the questions in this quiz are sure to rile … Weba from of drug tolerance in which patients who take a particular medication for an extended period can build up a tolerance to other medications in the same class cumulative effect an effect that occurs when several successive doses of a medication are administered or when absorption of a medication occurs faster than excretion or metabolism floor molding and trim