WebUpon induction, the recombination occurs in the NG2 positive cells (OPCs and pericytes). The membrane-bound GFP (mGFP) is selectively expressed in myelinating OLs, as it is under the control of ... WebCspg4-creERT2 activity in the Cortex (A) and Medulla (B). Imaging of Pdgfrβ-CreERT2 in the Cortex (C) (arrowhead points to mesangial cells (glomerulus), and arrows point to interstitial pericytes) in medulla (D). …

Expression of mGFP positive cells in the Cspg4-CreERt; mT/mG …

WebJul 1, 2024 · CSPG4 plays a central role in the oncogenic pathways required for malignant progression and metastatization. Thanks to these features and to its poor expression in adult healthy tissues, CSPG4 represents an ideal oncoantigen and thus an attractive target for anti-tumor immunotherapy. In this review we explore the potential of CSPG4 immune ... WebJun 25, 2024 · Protein kinase CK2 is a crucial regulator of endothelial cell proliferation, migration and sprouting during angiogenesis. However, it is still unknown whether this kinase additionally affects the angiogenic activity of other vessel-associated cells. In this study, we investigated the effect of CK2 inhibition on primary human pericytes. We found … simple white house

Optimization of tamoxifen-induced Cre activity and its effect …

WebØ Cspg4-201 gene has 10 exons, with the ATG start codon in exon1 and TGA stop codon in exon10. Ø We make Cspg4-CreERT2-P2A knockin mice via CRISPR/Cas9 system. … WebApr 5, 2024 · Sox9 transgenic mice combined the Cspg4-CreERT2, Rosa26 stopflox-tTA and TRE::Sox9 alleles, controls the Cspg4-CreERT2 and Rosa26 stopflox-tdTomato … WebArticle Snippet: Cspg4 CreERT2 mice were used to label cardiac pericytes during embryonic development and is a validated model to label Cspg4 expressing cells and … simple white kitchens